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主题:陈竺出面推H1N1疫苗,但本地医生自己也好像不愿意打 -- AK545

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家园 格林-巴利症候群,罕见但严重的流感疫苗负作用

1976年美国,美国建国200周年。1月在迪克斯堡,美国陆军在新泽西的一个训练中心。身强力壮的18岁新兵刘易斯戴维刘易斯,参加了在新泽西寒冷冬季的整夜行军。开始感到头晕、恶心、无力、发烧、肌肉疼痛:这些都只是流感的典型病症。他仍然背起50磅的背包,虽然发着烧,他仍强迫自己继续前进。几个小时后他倒下了。在到达基地医院几个小时后,刘易斯不治身死。

普通流感的特点是每年使成千上万的人得病,但是亡故的往往是老人、儿童。很少见到强壮的小伙子死于流感的。这在当时就引起了部分军队医生的注意。政府、专家和民众都有些担心1918年流感大爆发卷土重来,全国各地紧急动员,4000多万人,也就是当时人口的25%以上,都接种甲型H1N1型流感疫苗。

由于那种疫苗的副作用,后来500多人发展成为桂兰-巴尔综合症(Guillain-Barre syndrome),25人死亡。可是根据疾病防治中心(CDC)的资料,而原来估计可能造成美国超过5000万人生病的甲型H1N1型流感却没有爆发,全国最终只有200例甲型H1N1型流感,1人死亡。

以下引自英文Wiki 外链出处

GBS may be a rare side-effect of influenza vaccines, with an incidence of about one case per million vaccinations.[10] There were indeed reports of GBS affecting about 500 people who had received swine flu immunizations in the 1976 U.S. outbreak of swine flu — 25 of which resulted in death from severe pulmonary complications, leading the government to end that immunization campaign[11]. However, the role of the vaccine in these cases has remained unclear, partly because GBS had an unknown but very low incidence rate in the general population making it difficult to assess whether the vaccine was really increasing the risk for GBS. Later research have concluded to the absence of or to very small increase in the GBS risk due to the 1976 swine flu vaccine[12]. Besides the GBS may not have been directly due to the vaccine but to a bacterial contamination of the vaccine that triggered GBS.[13]

Since 1976, other influenza vaccines have not been linked to GBS, though as a precautionary principle caution is advised for certain individuals, particularly those with a history of GBS.[14][15]

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