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主题:31位国际学术同仁声援肖传国医生的公开信 -- 果酱

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  • 家园 31位国际学术同仁声援肖传国医生的公开信

    我先请教各位河友:

    方舟子质疑肖传国的学术成果是属于学术打假还是学术争论?

    学术打假和学术争论有什么区别?

    是不是质疑某人的某项学术成果,就可以认为自己在学术打假?

    此处下载原文PDF文档 [sci.rutgers.edu]

    Open letter in support of Chuan-Guo Xiao, M.D. from the

    International Academic Community

    September 29, 2010

    To all,

    We have all had the pleasure of knowing Dr. Chuan-Guo Xiao for many years. He is an

    internationally respected surgeon-scientist who has made major advances in the

    development of neuroregeneration to restore voiding and bowel function. Dr. Xiao

    performed groundbreaking animal research in the United States, demonstrating that a

    motor nerve that innervates the leg can be used to reinnervate the bladder and

    bowel. This reinnervation allows for development of a reflex to initiate bladder

    function. The results of his studies were published in peer-reviewed journals and

    other scientists have replicated Xiao’s findings confirming these results.

    Dr. Xiao eventually took the courageous step of moving from animal research to

    human studies and began performing the rerouting procedure on patients with spinal

    cord injury and spina bifida in China. Neurogenic bladder is life threatening in China

    due to a lack of both antimuscarinics and intermittent catheterization, and lessening

    the complications of neurogenic bladder would be considered a lifesaving success.

    Patients with neurogenic bladder and bowel suffer greatly and endure a host of issues

    such as urinary retention, incontinence, recurrent infections, renal insufficiency,

    fecal incontinence, constipation, and poor quality of life. For a procedure as

    complicated as nerve rerouting requiring nerve regeneration, one cannot expect

    normalization of bladder and bowel function to be the definition of success. What is

    important is that the benefits outweigh the risks of the procedure.

    Dr. Xiao published his clinical results in peer-reviewed journals and was twice

    honored by the Jack Lapides Essay Contest, one of the most respected international

    awards given to scientists who make major contributions to the field of neurourology.

    In 2008, he was named the Kelm Hjalmas Memorial Lecturer from the International

    Children’s Continence Society for his scientific achievements. Many of us have

    traveled to China to examine patients treated by Dr. Xiao and/or have been trained

    by him in the nerve rerouting surgery he invented. Dr. Xiao is a very skilled surgeon

    who is passionate about patient care and works tirelessly to train physicians around

    the world in performing his nerve rerouting procedure.

    In the United States, an independent and very rigorous pilot research trial was

    performed to test the safety and efficacy of this procedure. The one-year results

    were recently published in the Journal of Urology. At the 12-month follow-up visit, a

    cutaneous to bladder reflex was found in 7 of 9 spina bifida patients, confirming that

    rerouting does occur. This finding by itself is remarkable and Dr. Xiao should be

    commended. In addition, a number of patients demonstrated improvement in bladder

    and bowel function, which has continued to improve with longer patient follow-up.

    The 36-month results are currently being analyzed and will be reported in the near

    future. The pilot data was supportive of Dr. Xiao’s procedure, and now an NIH

    sponsored clinical trial is being conducted to further study lumbar to sacral nerve

    rerouting in spina bifida patients. In addition, similar procedures have been done

    worldwide, with Dr. Xiao helping to mentor the surgeons at each site.

    The Chinese people and government should be proud of Dr. Xiao for his dedication to

    his patients, his scientific achievements, and his willingness to train doctors around

    the world how to perform his surgery. The International scientific community was

    shocked to hear of Dr. Xiao’s arrest. Those of us who know Dr. Xiao well find it

    difficult to believe that he is involved in these attacks.

    Dr. Xiao is a compassionate man who is respected worldwide for his integrity and his

    innovative scientific contributions to society. We implore the Chinese government

    and authorities to treat Dr. Xiao fairly and to protect his human rights as these

    charges are investigated. Please strongly consider Dr. Xiao’s scientific and

    humanitarian contributions to the world as facts are gathered in this case.

    Sincerely,

    Kenneth M. Peters, MD

    Professor and Chairman of Urology

    Beaumont Hospital

    Royal Oak, Michigan USA

    Jack S. Elder, M.D.

    Chief of Urology, Henry Ford Health System

    Associate Director, Vattikuti Urology Institute

    Department of Urology,

    Children's Hospital of Michigan

    Detroit, MI USA

    Edwin A. Smith M.D.

    Assistant Clinical Professor of Urology

    Emory University School of Medicine

    Atlanta, Georgia USA

    Kevin M. Feber, MD, FAAP

    Beaumont Children's Hospital

    Royal Oak, MI USA

    Ananias C. Diokno, M.D., F.A.C.S.

    Executive Vice President & CMO

    Beaumont Hospital

    Royal Oak, Michigan 48073 USA

    Juan José de Benito

    Urologist

    Hospital Nacional de Clínicas

    Córdoba, Argentina.

    William E. Nantau B.Sc., CNIM

    Clinical Manager

    Clinical Neurophysiology Department

    Beaumont Hospital Royal Oak, MI USA

    Evan J Kass MD,FACS,FAAP

    Chief, Division of Pediatric Urology

    Beaumont Childrens Hospital

    Professor of Urology, Oakland University-William

    Beaumont School of Medicine

    USA

    Jacques Corcos MD.

    Professor of Urology, McGill University

    General Secretary of the International Continence

    Society

    Jewish General hospital

    3755 Cote Ste-Catherine

    Montreal, Quebec, Canada H3T 1E2

    Jose Gonzalez, M.D.

    Department of Urology

    Beaumont Hospital

    Royal Oak, Michigan USA

    Christopher Payne, MD

    Associate Professor of Urology

    Stanford University Medical School

    Stanford, CA 94305-5118 USA

    Kenneth I. Glassberg, MD

    Director, Division of Pediatric Urology

    Morgan Stanley Children's Hospital of New York-

    Presbyterian

    Professor of Urology, Columbia University

    College of Physicians and Surgeons

    3959 Broadway, CHN 1118 NY USA

    Earl Y. Cheng, MD

    Associate Professor of Urology

    Children’s Memorial Hospital

    Chicago, Illinois USA

    Professor of Surgery

    Senior Associate Scientist

    Director of Urology Research

    Divisions of Urology and

    Developmental & Stem Cell Biology

    The Hospital For Sick Children

    Institute of Medical Science

    University of Toronto

    Henri B. LOTTMANN, MD, FEBU, FEBPS,

    FRCS(england) FEBPU

    Paediatric urology unit

    Hopital Necker-Enfants-Malades

    149, rue de Sèvres

    75015 Paris, France

    Dr. Amrish Vaidya MS. MCh.

    Consultant Paediatric Surgeon,

    Kokilaben Dhirubhai Ambani Hospital,

    4 Bungalows, Andheri W, Mumbai, India

    Marc Cendron, MD

    Associate Professor in Urology

    Harvard Medical School

    Children’s Hospital Boston

    Boston, MA USA

    Stuart B. Bauer, MD

    Associate Director, Neurourology

    Professor of Urology

    Harvard Medical School

    Children’s Hospital Boston

    Boston, MA USA

    Edmond T. Gonzales, Jr., MD

    Professor of Urology

    Baylor College of Medicine

    Houston TX USA

    Richard Macchia, MD FACS

    SUNY Distinguished Teaching Professor

    Cleveland Clinic, Florida

    Benjamin Girdler, MD

    Urology Center of the Rockies

    Fort Collins, Colorado USA

    William C. de Groat, Ph.D.

    Professor of Pharmacology

    University of Pittsburgh

    Pittsburgh, PA USA

    Michael R. Ruggieri, Sr., Ph.D.

    Director of Urologic Research

    Temple University School of Medicine

    Philadelphia, PA USA

    Stanley J Kogan MD

    Chief, Pediatric Urology

    Children's Hospital at Montefiore

    Bronx NY USA

    Anthony Caldamone, MD

    University Urologic Associates, Inc.

    2 Dudley St Ste 185

    Providence, RI 02905 USA

    Yves Homsy MD, FRCSC, FAAP

    Clinical Professor of Urological Surgery and

    Pediatrics

    University of South Florida

    Children's Urology Group

    5507 E. Longboat Blvd

    Tampa FL 33615 USA

    Dr. Enrique Turina

    Professor of urology of the National University of

    Buenos Aires

    Chief of section Urology of Instituto de

    Rehabilitación

    Government of Buenos Aires, Argentina.

    Dr. Angel Ozón

    Urologist of the Instituto de Rehabilitación of Buenos

    Aires

    Dr. Daniel Ekizian

    Urologist of Instituto de Rehabilitación.

    Professor Dr. med. Karl-Dietrich Sievert

    Vice Chair

    Prof. of Urology, Director - Uro-oncology,

    Neurourology, Incontinence, & Reconstructive

    Urology

    Department of Urology University of Tuebingen

    D72076 Tuebingen, Germany

    Holly Gilmer, MD

    Chief of Pediatric Neurosurgery

    Beaumont Hospital

    Royal Oak, Michigan USA

    Yegappan Lakshmanan, MD

    Chief, Pediatric Urology

    Children’s Hospital of Michigan

    Detroit, MI USA

    国际学术同仁声援肖传国医生的公开信

    2010年9月29日

    致所有人:

    我们都有幸认识肖传国大夫多年。他是一位受国际学术界尊敬的外科医生和科学家,在恢复(脊椎损伤病人的)排尿和排便功能的神经再生研究中,他取得了重大进展。肖传国医生在美国完成了开创性的动物实验研究,阐明支配大腿的运动神经可以用来绕接支配膀胱和排便。这个绕接可以形成一个反射作用(反射弧)来启动来膀胱功能。他研究的成果已经多次发表在同行评议的国际科学期刊上。其他的科学家也已经重复并证实了肖医生的这些研究结果。

    肖医生最终鼓起勇气将动物实验研究的成果转化到临床试验上,在中国的脊柱损伤和脊柱裂病人身上开展神经绕接(神经通路重建,即反射弧)手术。在中国,由于缺乏抗痉挛药物antimuscarinics和间歇性导尿术(自插导尿管),神经性膀胱功能障碍成为一种威胁生命的疾病。能缓解神经性膀胱功能障碍的并发症的疗法,就是一种能够拯救生命的成功。神经性膀胱和排大便功能障碍患者的病情是很痛苦的,包括遭受尿潴留、尿失禁、反复感染、肾功能不全、大便失禁、便秘等,生活质量极差。神经通路重建手术是一个非常复杂的手术,需要神经的再生。不应当把手术的成功定义为完全恢复排便排尿功能。这项手术的重点在于收益超过风险。

    肖医生的临床研究成果发表在多种学术刊物上,并两次获得Jack Lapides佳作奖,这是奖励在神经泌尿科学界作出重要贡献的科学家的最崇高的国际性大奖之一。2008年,因为他的科学成就,肖医生还获得了国际儿童排尿节制学会颁发的Kelm Hjalmas演讲者(受邀做大会主题发言)荣誉。我们当中的许多人都曾经到中国去检视肖医生治疗过的患者的情况,观摩或者学习他发明的神经通路重建手术。肖医生是一位非常有经验的外科医生,他对患者热情照顾,不知疲倦地培训来自世界各地的医生们,来推广他的神经通路重建手术。

    在美国,已经开展过一项独立而且严格的先期试验来检验这项手术的安全性和效益。术后一年的治疗结果最近发表在《泌尿科学杂志》( Journal of Urology)上。在12个月的随访期间,在9位脊髓裂患者中,有7位患者,观察到皮下至膀胱的神经反射弧的构建成立,证明神经通路重建手术的确起了作用。这个成绩是了不起的,肖医生应该得到嘉奖。并且,一部分患者已经展现出大小便排便功能的改善,并将随时间推移而变得更好。术后36个月的成果正在分析中,不久就会发表。该先期试验的数据是支持“肖氏手术”的,现在受NIH(美国国立卫生研究院)资助的临床试验正在开展,以进一步在脊髓裂患者中研究腰椎至骶神经通路重建。还有,在肖医生的帮助和指导下,类似的临床试验也在世界范围内开展。

    中国人民和政府应该为肖医生对病人所作出的贡献、对他的科学成就,和他在世界上培训医生以推广这项手术的诚意而自豪。国际科学界对肖医生被拘捕的消息感到震惊。我们这些了解肖医生的人,都对他涉入此案感到难以置信。

    肖医生是一个极富同情心的绅士,他的诚实和对本学科作出的开创性的科学成就广受世界同行的尊敬。我们恳请中国政府和有关权威机构公正对待肖大夫,并在案情调查期间保障他的基本人权。在此事件中,请重视肖大夫对世界所作出的科学和人道主义事业的贡献。

    谨致

    Kenneth M. Peters, MD

    Professor and Chairman of Urology

    Beaumont Hospital

    Royal Oak, Michigan

    (美国Beaumont医院泌尿科主任)

    Jack S. Elder, M.D.

    Chief of Urology, Henry Ford Health System

    Associate Director, Vattikuti Urology Institute

    Department of Urology, Children's Hospital of Michigan

    Clinical Professor of Urology, Case School of Medicine

    (美国密西根儿童医院泌尿科主任)

    Edwin A. Smith M.D.

    Assistant Clinical Professor of Urology

    Emory University School of Medicine

    Atlanta, Georgia

    (美国艾默里大学医学院临床助理教授)

    Kevin M. Feber, MD, FAAP

    Board Certified in Pediatric Urology

    Comprehensive Urology

    William Beaumont Children's Hospital

    (美国William Beaumont儿童医院医生)

    Ananias C. Diokno, M.D., F.A.C.S.Executive Vice President & CMOBeaumont HospitalRoyal Oak, Michigan 48073 USA

    (美国Beaumont医院执行副总裁)

    Juan José de Benito

    Urologist

    Hospital Nacional de Clínicas

    Córdoba, Argentina.

    (阿根廷国立医院)

    William E. Nantau B.Sc., CNIMClinical ManagerClinical Neurophysiology DepartmentBeaumont Hospital Royal Oak

    (美国Beaumont医院临床神经生理科临床主管)

    Evan J Kass MD,FACS,FAAPChief, Division of Pediatric UrologyBeaumont Childrens HospitalProfessor of Urology, Oakland University-William Beaumont School of Medicine

    (美国Beaumont儿童医院泌尿科主任,奥克兰大学医学院教授)

    Jacques Corcos MD.Professor of Urology, McGill UniversityGeneral Secretary of the International Continence SocietyJewish General hospital3755 Cote Ste-CatherineMontreal, Quebec, Canada H3T 1E2

    (加拿大麦基尔大学泌尿学教授,国际儿童排尿节制学会秘书长)

    Jose Gonzalez, M.D.

    Department of Urology

    Beaumont Hospital

    Royal Oak, Michigan

    (美国Beaumont医院泌尿科医生)

    Christopher Payne, MD

    Associate Professor of Urology

    Stanford University Medical School

    Stanford, CA 94305-5118

    (美国斯坦福大学医学院泌尿学副教授)

    Kenneth I. Glassberg, MD

    Director, Division of Pediatric Urology

    Morgan Stanley Children's Hospital of New York-Presbyterian

    Professor of Urology, Columbia University

    College of Physicians and Surgeons

    3959 Broadway, CHN 1118

    (美国哥伦比亚大学医学院泌尿学教授,儿童泌尿学分科主任)

    Earl Y. Cheng, MD

    Associate Professor of Urology

    Children’s Memorial Hospital

    Chicago, Illinois

    (美国芝加哥儿童医院泌尿学副教授)

    Darius J. Bagli, MDCM

    Professor of Surgery

    Senior Associate Scientist

    Director of Urology Research

    Divisions of Urology and

    Developmental & Stem Cell Biology

    The Hospital For Sick Children

    Institute of Medical Science

    University of Toronto

    (加拿大多伦多大学外科学教授,泌尿学研究主任)

    Henri B. LOTTMANN, MD, FEBU, FEBPS, FRCS(england) FEBPU

    Paediatric urology unit

    Hopital Necker-Enfants-Malades

    149, rue de Sèvres

    75015 Paris

    France

    (法国Necker-Enfants-Malades医院儿童泌尿科医生)

    Dr. Amrish Vaidya MS. MCh.Consultant Paediatric Surgeon,Kokilaben Dhirubhai Ambani Hospital,4 Bungalows, Andheri W, Mumbai, India

    (印度Kokilaben Dhirubhai Ambani医院医生)

    Marc Cendron, MD

    Associate Professor in Urology

    Harvard Medical School

    Children’s Hospital Boston

    Boston, MA

    (美国哈佛大学医学院泌尿学副教授)

    Stuart B. Bauer, MD

    Associate Director, Neurourology

    Professor of Urology

    Harvard Medical School

    Children’s Hospital Boston

    Boston, MA

    (美国哈佛大学医学院泌尿学教授,波士顿儿童医院神经泌尿科副主任)

    Edmond T. Gonzales, Jr., MD

    Professor of Urology

    Baylor College of Medicine

    (美国贝勒医学院泌尿学教授)

    Richard Macchia, MD FACS

    SUNY Distinguished Teaching Professor

    Cleveland Clinic, Florida

    (美国Cleveland临床中心教授)

    Benjamin Girdler, MD

    Urology Center of the Rockies

    Fort Collins, Colorado

    (美国科罗拉多洛基泌尿中心医生)

    William C. de Groat, Ph.D.

    Professor of Pharmacology

    University of Pittsburgh

    (美国匹兹堡大学药理学教授)

    Michael R. Ruggieri, Sr., Ph.D.

    Director of Urologic Research

    Temple University School of Medicine

    (美国坦普大学医学院泌尿学研究主任)

    Stanley J Kogan MDChief, Pediatric UrologyChildren's Hospital at MontefioreBronx NY USA

    (美国Montefiore儿童医院儿童泌尿科主任)

    Anthony Caldamone, MD

    University Urologic Associates, Inc.2 Dudley St Ste 185Providence, RI 02905

    (美国布朗大学泌尿学中心医生)

    Yves Homsy MD, FRCSC, FAAP Clinical Professor of Urological Surgery and Pediatrics University of South Florida Children's Urology Group 5507 E. Longboat Blvd Tampa FL 33615

    (美国南弗罗里达大学临床泌尿学教授)

    Dr. Enrique Turina

    Professor of urology of the National University of Buenos Aires

    Chief of section Urology of Instituto de Rehabilitación

    Government of Buenos Aires, Argentina.

    (阿根廷国立Buenos Aires大学泌尿学教授)

    Dr. Angel Ozón

    Urologist of the Instituto de Rehabilitación of Buenos Aires

    (阿根廷国立Buenos Aires大学泌尿学医生)

    Dr. Daniel Ekizian

    Urologist of Instituto de Rehabilitación.

    (阿根廷国立Buenos Aires大学泌尿学医生)

    Professor Dr. med. Karl-Dietrich Sievert

    Vice Chair Prof. of Urology, Director - Uro-oncology, Neurourology, Incontinence, & Reconstructive Urology Department of Urology University of Tuebingen D72076 Tuebingen, Germany

    (德国Tuebingen大学泌尿学教授、主任)

    Holly Gilmer, MD

    Chief of Pediatric Neurosurgery

    Beaumont Hospital

    Royal Oak, Michigan

    (美国Beaumont医院儿童神经外科主任)

    Yegappan Lakshmanan, MD

    Chief, Pediatric Urology

    Children’s Hospital of Michigan

    (美国密西根儿童医院儿童泌尿科主任)

    外链出处


    本帖一共被 1 帖 引用 (帖内工具实现)
    • 家园 肖锤子要先进监狱, 支持他在监狱里继续学术争论

      抡锤子是个法律问题, 不管是肖锤, 还是方舟子, 都要守法. 违法都要受处罚.

      学术争论是另一件事.

    • 家园 学术争论和学术打假的分野在哪里

      学术争论,是双方诚实地都用科学证据说话。

      学术打假,是有人伪造证据,被提出质疑,然后恼羞成怒,用锤子说话。

      你的倾向性已经很明显了,别躲躲闪闪的。你要是跟肖锤子不是一伙的算我瞎眼。

      • 家园 学术争论,双方要有可以沟通的学术背景,否则隔行如

        隔山,有可能会鸡同鸭讲.

        而方是否具备了真正了解肖的工作的能力,我有点怀疑.(他关于中医的一些观点侧面的印证了这点.)

        如果是这样,学术打假方是不够资格的,这样也容易理解一个内行被一个外行纠缠不清时的心态.

        • 家园 送花谢宝,认同阁下观点

          大多数时候,老方也就是做一点简历打假还够格--他似乎有很多时间来做这个工作。

          至于说学术打假,我也怀疑他的能力。别的我不知道,他用自己半吊子的病毒/免疫学知识来反中医,在我看来是比较搞笑的。

    • 家园 一万个P加起来,也只是P。

      方舟子不是医学家,他对肖的批评和指责有多少能站住脚,没法评论,老肖的学术水平到底有多高,恐怕业外人士也很难下个定论。河里高手如云,又有几个能去给他下个判断呢?

      但是肖被捕的原因是雇凶伤人,按照中国法律的规定,是违法乃至犯罪的行为,就是爱因斯坦或者钱学森做了这种事,也是应该依法处理。当然在上述专家们所在的国家是如何规定的,就不得而知了。

      ------------------俺也分界线一次-----------------------------

      我们这些了解肖医生的人,都对他涉入此案感到难以置信。

      我们恳请中国政府和有关权威机构公正对待肖大夫,并在案情调查期间保障他的基本人权。

      这几句话,触动了我义和团式的敏感:他们正站在某个高度,怀着某种优越感和多多少少的蔑视,质疑中国的执法和司法程序。

      • 家园 1

        那么多海外党 随便去个问问签名信里面出现过的外国佬这签名信是真是假 给他们签名的原件上面写的是什么比研究医学快捷多了。语法这种东西还是退一步的东西。

    • 家园 反方意见:国外同行专家对美国肖氏手术临床试验结果的评价

      国外同行专家对美国肖氏手术临床试验结果的评价

      不管怎么说,“成功率超过85%”被证明是个吹嘘,这可是在拿人体做实验呀

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虚拟的网络,真实的人。天南地北客,相逢皆朋友

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